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ChemicalAffectsGeneAssociation

Describes an effect that a chemical has on a gene or gene product (e.g. an impact of on its abundance, activity, localization, processing, expression, etc.)

classDiagram Association <|-- ChemicalAffectsGeneAssociation ChemicalAffectsGeneAssociation : aggregator_knowledge_source ChemicalAffectsGeneAssociation : anatomical_context_qualifier ChemicalAffectsGeneAssociation : category ChemicalAffectsGeneAssociation : causal_mechanism_qualifier ChemicalAffectsGeneAssociation : description ChemicalAffectsGeneAssociation : has_attribute ChemicalAffectsGeneAssociation : has_evidence ChemicalAffectsGeneAssociation : id ChemicalAffectsGeneAssociation : iri ChemicalAffectsGeneAssociation : knowledge_source ChemicalAffectsGeneAssociation : name ChemicalAffectsGeneAssociation : negated ChemicalAffectsGeneAssociation : object ChemicalAffectsGeneAssociation : object_aspect_qualifier ChemicalAffectsGeneAssociation : object_context_qualifier ChemicalAffectsGeneAssociation : object_form_or_variant_qualifier ChemicalAffectsGeneAssociation : object_part_qualifier ChemicalAffectsGeneAssociation : original_knowledge_source ChemicalAffectsGeneAssociation : predicate ChemicalAffectsGeneAssociation : primary_knowledge_source ChemicalAffectsGeneAssociation : publications ChemicalAffectsGeneAssociation : qualified_predicate ChemicalAffectsGeneAssociation : qualifiers ChemicalAffectsGeneAssociation : source ChemicalAffectsGeneAssociation : subject ChemicalAffectsGeneAssociation : subject_aspect_qualifier ChemicalAffectsGeneAssociation : subject_context_qualifier ChemicalAffectsGeneAssociation : subject_derivative_qualifier ChemicalAffectsGeneAssociation : subject_direction_qualifier ChemicalAffectsGeneAssociation : subject_form_or_variant_qualifier ChemicalAffectsGeneAssociation : subject_part_qualifier ChemicalAffectsGeneAssociation : timepoint ChemicalAffectsGeneAssociation : type

Parent Classes

Slots

Name Description
aggregator_knowledge_source An intermediate aggregator resource from which knowledge expressed in an Association was retrieved downstream of the original source, on its path to its current serialized form.
anatomical_context_qualifier A statement qualifier representing an anatomical location where an relationship expressed in an association took place (can be a tissue, cell type, or subcellular location).
category Name of the high level ontology class in which this entity is categorized. Corresponds to the label for the biolink entity type class. In a neo4j database this MAY correspond to the neo4j label tag. In an RDF database it should be a biolink model class URI. This field is multi-valued. It should include values for ancestors of the biolink class; for example, a protein such as Shh would have category values biolink:Protein, biolink:GeneProduct, biolink:MolecularEntity, etc. In an RDF database, nodes will typically have an rdf:type triples. This can be to the most specific biolink class, or potentially to a class more specific than something in biolink. For example, a sequence feature f may have a rdf:type assertion to a SO class such as TF_binding_site, which is more specific than anything in biolink. Here we would have categories {biolink:GenomicEntity, biolink:MolecularEntity, biolink:NamedThing}
causal_mechanism_qualifier A statement qualifier representing a type of molecular control mechanism through which an effect of a chemical on a gene or gene product is mediated (e.g. 'agonism', 'inhibition', 'allosteric modulation', 'channel blocker')
description a human-readable description of an entity
has_attribute connects any entity to an attribute
has_evidence connects an association to an instance of supporting evidence
id A unique identifier for an entity. Must be either a CURIE shorthand for a URI or a complete URI
iri An IRI for an entity. This is determined by the id using expansion rules.
knowledge_source An Information Resource from which the knowledge expressed in an Association was retrieved, directly or indirectly. This can be any resource through which the knowledge passed on its way to its currently serialized form. In practice, implementers should use one of the more specific subtypes of this generic property.
name A human-readable name for an attribute or entity.
negated if set to true, then the association is negated i.e. is not true
object connects an association to the object of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.
object_aspect_qualifier None
object_context_qualifier None
object_form_or_variant_qualifier None
object_part_qualifier None
original_knowledge_source None
predicate A high-level grouping for the relationship type. AKA minimal predicate. This is analogous to category for nodes.
primary_knowledge_source The most upstream source of the knowledge expressed in an Association that an implementer can identify (may or may not be the 'original' source).
publications connects an association to publications supporting the association
qualified_predicate predicate to be used in an association when subject and object qualifiers are present and the full reading of the statement requires a qualification to the predicate in use in order to refine or increase the specificity of the full statement reading
qualifiers connects an association to qualifiers that modify or qualify the meaning of that association
source None
subject connects an association to the subject of the association. For example, in a gene-to-phenotype association, the gene is subject and phenotype is object.
subject_aspect_qualifier None
subject_context_qualifier None
subject_derivative_qualifier None
subject_direction_qualifier None
subject_form_or_variant_qualifier None
subject_part_qualifier None
timepoint a point in time
type None

Mappings

Mapping Type Mapped Value
self ['biolink:ChemicalAffectsGeneAssociation']
native ['biolink:ChemicalAffectsGeneAssociation']