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Class: DruggableGeneToDiseaseAssociation

URI: biolink:DruggableGeneToDiseaseAssociation

classDiagram class DruggableGeneToDiseaseAssociation EntityToDiseaseAssociationMixin <|-- DruggableGeneToDiseaseAssociation GeneToEntityAssociationMixin <|-- DruggableGeneToDiseaseAssociation GeneToDiseaseAssociation <|-- DruggableGeneToDiseaseAssociation DruggableGeneToDiseaseAssociation : aggregator_knowledge_source DruggableGeneToDiseaseAssociation : category DruggableGeneToDiseaseAssociation : description DruggableGeneToDiseaseAssociation : frequency_qualifier DruggableGeneToDiseaseAssociation : has_attribute DruggableGeneToDiseaseAssociation --|> attribute : has_attribute DruggableGeneToDiseaseAssociation : has_count DruggableGeneToDiseaseAssociation : has_evidence DruggableGeneToDiseaseAssociation --|> DruggableGeneCategoryEnum : has_evidence DruggableGeneToDiseaseAssociation : has_percentage DruggableGeneToDiseaseAssociation : has_quotient DruggableGeneToDiseaseAssociation : has_total DruggableGeneToDiseaseAssociation : id DruggableGeneToDiseaseAssociation : iri DruggableGeneToDiseaseAssociation : knowledge_source DruggableGeneToDiseaseAssociation : name DruggableGeneToDiseaseAssociation : negated DruggableGeneToDiseaseAssociation : object DruggableGeneToDiseaseAssociation --|> disease : object DruggableGeneToDiseaseAssociation : object_category DruggableGeneToDiseaseAssociation --|> ontology class : object_category DruggableGeneToDiseaseAssociation : object_category_closure DruggableGeneToDiseaseAssociation --|> ontology class : object_category_closure DruggableGeneToDiseaseAssociation : object_closure DruggableGeneToDiseaseAssociation : object_direction_qualifier DruggableGeneToDiseaseAssociation --|> DirectionQualifierEnum : object_direction_qualifier DruggableGeneToDiseaseAssociation : object_label_closure DruggableGeneToDiseaseAssociation : object_namespace DruggableGeneToDiseaseAssociation : onset_qualifier DruggableGeneToDiseaseAssociation --|> onset : onset_qualifier DruggableGeneToDiseaseAssociation : original_object DruggableGeneToDiseaseAssociation : original_predicate DruggableGeneToDiseaseAssociation : original_subject DruggableGeneToDiseaseAssociation : predicate DruggableGeneToDiseaseAssociation : primary_knowledge_source DruggableGeneToDiseaseAssociation : publications DruggableGeneToDiseaseAssociation --|> publication : publications DruggableGeneToDiseaseAssociation : qualifiers DruggableGeneToDiseaseAssociation --|> ontology class : qualifiers DruggableGeneToDiseaseAssociation : retrieval_source_ids DruggableGeneToDiseaseAssociation --|> retrieval source : retrieval_source_ids DruggableGeneToDiseaseAssociation : severity_qualifier DruggableGeneToDiseaseAssociation --|> severity value : severity_qualifier DruggableGeneToDiseaseAssociation : sex_qualifier DruggableGeneToDiseaseAssociation --|> biological sex : sex_qualifier DruggableGeneToDiseaseAssociation : subject DruggableGeneToDiseaseAssociation --|> gene or gene product : subject DruggableGeneToDiseaseAssociation : subject_aspect_qualifier DruggableGeneToDiseaseAssociation --|> GeneOrGeneProductOrChemicalEntityAspectEnum : subject_aspect_qualifier DruggableGeneToDiseaseAssociation : subject_category DruggableGeneToDiseaseAssociation --|> ontology class : subject_category DruggableGeneToDiseaseAssociation : subject_category_closure DruggableGeneToDiseaseAssociation --|> ontology class : subject_category_closure DruggableGeneToDiseaseAssociation : subject_closure DruggableGeneToDiseaseAssociation : subject_label_closure DruggableGeneToDiseaseAssociation : subject_namespace DruggableGeneToDiseaseAssociation : timepoint DruggableGeneToDiseaseAssociation : type

Inheritance

Slots

Name Cardinality and Range Description Inheritance
subject_aspect_qualifier 0..1
GeneOrGeneProductOrChemicalEntityAspectEnum
GeneToDiseaseOrPhenotypicFeatureAssociation
object_direction_qualifier 0..1
DirectionQualifierEnum
GeneToDiseaseOrPhenotypicFeatureAssociation
sex_qualifier 0..1
BiologicalSex
a qualifier used in a phenotypic association to state whether the association... EntityToPhenotypicFeatureAssociationMixin
subject 1..1
GeneOrGeneProduct
gene in which variation is correlated with the disease in a protective manner... Association
predicate 1..1
PredicateType
A high-level grouping for the relationship type Association
object 1..1
Disease
disease Association
negated 0..1
Boolean
if set to true, then the association is negated i Association
qualifiers 0..*
OntologyClass
connects an association to qualifiers that modify or qualify the meaning of t... Association
publications 0..*
Publication
One or more publications that report the statement expressed in an Associati... Association
has_evidence 0..*
DruggableGeneCategoryEnum
connects an association to an instance of supporting evidence Association
knowledge_source 0..1
String
An Information Resource from which the knowledge expressed in an Association ... Association
primary_knowledge_source 0..1
String
The most upstream source of the knowledge expressed in an Association that an... Association
aggregator_knowledge_source 0..*
String
An intermediate aggregator resource from which knowledge expressed in an Asso... Association
timepoint 0..1
TimeType
a point in time Association
original_subject 0..1
String
used to hold the original subject of a relation (or predicate) that an extern... Association
original_predicate 0..1
Uriorcurie
used to hold the original relation/predicate that an external knowledge sourc... Association
original_object 0..1
String
used to hold the original object of a relation (or predicate) that an externa... Association
subject_category 0..1
OntologyClass
Used to hold the biolink class/category of an association Association
object_category 0..1
OntologyClass
Used to hold the biolink class/category of an association Association
subject_closure 0..*
String
Used to hold the subject closure of an association Association
object_closure 0..*
String
Used to hold the object closure of an association Association
subject_category_closure 0..*
OntologyClass
Used to hold the subject category closure of an association Association
object_category_closure 0..*
OntologyClass
Used to hold the object category closure of an association Association
subject_namespace 0..1
String
Used to hold the subject namespace of an association Association
object_namespace 0..1
String
Used to hold the object namespace of an association Association
subject_label_closure 0..*
String
Used to hold the subject label closure of an association Association
object_label_closure 0..*
String
Used to hold the object label closure of an association Association
retrieval_source_ids 0..*
RetrievalSource
A list of retrieval sources that served as a source of knowledge expressed in... Association
id 1..1
String
A unique identifier for an entity Entity
iri 0..1
IriType
An IRI for an entity Entity
category 0..*
CategoryType
Name of the high level ontology class in which this entity is categorized Entity
type 0..*
String
rdf:type of biolink:Association should be fixed at rdf:Statement Entity
name 0..1
LabelType
A human-readable name for an attribute or entity Entity
description 0..1
NarrativeText
a human-readable description of an entity Entity
has_attribute 0..*
Attribute
connects any entity to an attribute Entity
has_count 0..1
Integer
number of things with a particular property FrequencyQuantifier
has_total 0..1
Integer
total number of things in a particular reference set FrequencyQuantifier
has_quotient 0..1
Double
FrequencyQuantifier
has_percentage 0..1
Double
equivalent to has quotient multiplied by 100 FrequencyQuantifier
severity_qualifier 0..1
SeverityValue
a qualifier used in a phenotypic association to state how severe the phenotyp... EntityToFeatureOrDiseaseQualifiersMixin
onset_qualifier 0..1
Onset
a qualifier used in a phenotypic association to state when the phenotype appe... EntityToFeatureOrDiseaseQualifiersMixin
frequency_qualifier 0..1
FrequencyValue
a qualifier used in a phenotypic association to state how frequent the phenot... FrequencyQualifierMixin

Identifier and Mapping Information

Schema Source

  • from schema: https://w3id.org/biolink/biolink-model

Mappings

Mapping Type Mapped Value
self biolink:DruggableGeneToDiseaseAssociation
native biolink:DruggableGeneToDiseaseAssociation

LinkML Source

Direct

name: druggable gene to disease association
from_schema: https://w3id.org/biolink/biolink-model
is_a: gene to disease association
mixins:
- entity to disease association mixin
- gene to entity association mixin
slot_usage:
  subject:
    name: subject
    description: gene in which variation is correlated with the disease in a protective
      manner, or if the product produced by the gene can be targeted by a small molecule
      and this leads to a protective or improving disease state.
    domain_of:
    - association
    range: gene or gene product
  predicate:
    name: predicate
    domain_of:
    - predicate mapping
    - association
    subproperty_of: target for
  has evidence:
    name: has evidence
    domain_of:
    - association
    range: DruggableGeneCategoryEnum
defining_slots:
- subject
- object
- predicate