Class: GeneAsAModelOfDiseaseAssociation
URI: biolink:GeneAsAModelOfDiseaseAssociation
classDiagram
class GeneAsAModelOfDiseaseAssociation
ModelToDiseaseAssociationMixin <|-- GeneAsAModelOfDiseaseAssociation
EntityToDiseaseAssociationMixin <|-- GeneAsAModelOfDiseaseAssociation
GeneToDiseaseAssociation <|-- GeneAsAModelOfDiseaseAssociation
GeneAsAModelOfDiseaseAssociation : aggregator_knowledge_source
GeneAsAModelOfDiseaseAssociation : category
GeneAsAModelOfDiseaseAssociation : description
GeneAsAModelOfDiseaseAssociation : frequency_qualifier
GeneAsAModelOfDiseaseAssociation : has_attribute
GeneAsAModelOfDiseaseAssociation --|> attribute : has_attribute
GeneAsAModelOfDiseaseAssociation : has_count
GeneAsAModelOfDiseaseAssociation : has_evidence
GeneAsAModelOfDiseaseAssociation --|> evidence type : has_evidence
GeneAsAModelOfDiseaseAssociation : has_percentage
GeneAsAModelOfDiseaseAssociation : has_quotient
GeneAsAModelOfDiseaseAssociation : has_total
GeneAsAModelOfDiseaseAssociation : id
GeneAsAModelOfDiseaseAssociation : iri
GeneAsAModelOfDiseaseAssociation : knowledge_source
GeneAsAModelOfDiseaseAssociation : name
GeneAsAModelOfDiseaseAssociation : negated
GeneAsAModelOfDiseaseAssociation : object
GeneAsAModelOfDiseaseAssociation --|> disease : object
GeneAsAModelOfDiseaseAssociation : object_category
GeneAsAModelOfDiseaseAssociation --|> ontology class : object_category
GeneAsAModelOfDiseaseAssociation : object_category_closure
GeneAsAModelOfDiseaseAssociation --|> ontology class : object_category_closure
GeneAsAModelOfDiseaseAssociation : object_closure
GeneAsAModelOfDiseaseAssociation : object_direction_qualifier
GeneAsAModelOfDiseaseAssociation --|> DirectionQualifierEnum : object_direction_qualifier
GeneAsAModelOfDiseaseAssociation : object_label_closure
GeneAsAModelOfDiseaseAssociation : object_namespace
GeneAsAModelOfDiseaseAssociation : onset_qualifier
GeneAsAModelOfDiseaseAssociation --|> onset : onset_qualifier
GeneAsAModelOfDiseaseAssociation : original_object
GeneAsAModelOfDiseaseAssociation : original_predicate
GeneAsAModelOfDiseaseAssociation : original_subject
GeneAsAModelOfDiseaseAssociation : predicate
GeneAsAModelOfDiseaseAssociation : primary_knowledge_source
GeneAsAModelOfDiseaseAssociation : publications
GeneAsAModelOfDiseaseAssociation --|> publication : publications
GeneAsAModelOfDiseaseAssociation : qualifiers
GeneAsAModelOfDiseaseAssociation --|> ontology class : qualifiers
GeneAsAModelOfDiseaseAssociation : retrieval_source_ids
GeneAsAModelOfDiseaseAssociation --|> retrieval source : retrieval_source_ids
GeneAsAModelOfDiseaseAssociation : severity_qualifier
GeneAsAModelOfDiseaseAssociation --|> severity value : severity_qualifier
GeneAsAModelOfDiseaseAssociation : sex_qualifier
GeneAsAModelOfDiseaseAssociation --|> biological sex : sex_qualifier
GeneAsAModelOfDiseaseAssociation : subject
GeneAsAModelOfDiseaseAssociation --|> gene or gene product : subject
GeneAsAModelOfDiseaseAssociation : subject_aspect_qualifier
GeneAsAModelOfDiseaseAssociation --|> GeneOrGeneProductOrChemicalEntityAspectEnum : subject_aspect_qualifier
GeneAsAModelOfDiseaseAssociation : subject_category
GeneAsAModelOfDiseaseAssociation --|> ontology class : subject_category
GeneAsAModelOfDiseaseAssociation : subject_category_closure
GeneAsAModelOfDiseaseAssociation --|> ontology class : subject_category_closure
GeneAsAModelOfDiseaseAssociation : subject_closure
GeneAsAModelOfDiseaseAssociation : subject_label_closure
GeneAsAModelOfDiseaseAssociation : subject_namespace
GeneAsAModelOfDiseaseAssociation : timepoint
GeneAsAModelOfDiseaseAssociation : type
Inheritance
- Entity
- Association
- GeneToDiseaseOrPhenotypicFeatureAssociation [ EntityToPhenotypicFeatureAssociationMixin GeneToEntityAssociationMixin]
- GeneToDiseaseAssociation [ EntityToDiseaseAssociationMixin GeneToEntityAssociationMixin]
- GeneAsAModelOfDiseaseAssociation [ ModelToDiseaseAssociationMixin EntityToDiseaseAssociationMixin]
- GeneToDiseaseAssociation [ EntityToDiseaseAssociationMixin GeneToEntityAssociationMixin]
- GeneToDiseaseOrPhenotypicFeatureAssociation [ EntityToPhenotypicFeatureAssociationMixin GeneToEntityAssociationMixin]
- Association
Slots
Name | Cardinality and Range | Description | Inheritance |
---|---|---|---|
subject_aspect_qualifier | 0..1 GeneOrGeneProductOrChemicalEntityAspectEnum |
GeneToDiseaseOrPhenotypicFeatureAssociation | |
object_direction_qualifier | 0..1 DirectionQualifierEnum |
GeneToDiseaseOrPhenotypicFeatureAssociation | |
sex_qualifier | 0..1 BiologicalSex |
a qualifier used in a phenotypic association to state whether the association... | EntityToPhenotypicFeatureAssociationMixin |
subject | 1..1 GeneOrGeneProduct |
A gene that has a role in modeling the disease | Association |
predicate | 1..1 PredicateType |
The relationship to the disease | Association |
object | 1..1 Disease |
disease | Association |
negated | 0..1 Boolean |
if set to true, then the association is negated i | Association |
qualifiers | 0..* OntologyClass |
connects an association to qualifiers that modify or qualify the meaning of t... | Association |
publications | 0..* Publication |
One or more publications that report the statement expressed in an Associati... | Association |
has_evidence | 0..* EvidenceType |
connects an association to an instance of supporting evidence | Association |
knowledge_source | 0..1 String |
An Information Resource from which the knowledge expressed in an Association ... | Association |
primary_knowledge_source | 0..1 String |
The most upstream source of the knowledge expressed in an Association that an... | Association |
aggregator_knowledge_source | 0..* String |
An intermediate aggregator resource from which knowledge expressed in an Asso... | Association |
timepoint | 0..1 TimeType |
a point in time | Association |
original_subject | 0..1 String |
used to hold the original subject of a relation (or predicate) that an extern... | Association |
original_predicate | 0..1 Uriorcurie |
used to hold the original relation/predicate that an external knowledge sourc... | Association |
original_object | 0..1 String |
used to hold the original object of a relation (or predicate) that an externa... | Association |
subject_category | 0..1 OntologyClass |
Used to hold the biolink class/category of an association | Association |
object_category | 0..1 OntologyClass |
Used to hold the biolink class/category of an association | Association |
subject_closure | 0..* String |
Used to hold the subject closure of an association | Association |
object_closure | 0..* String |
Used to hold the object closure of an association | Association |
subject_category_closure | 0..* OntologyClass |
Used to hold the subject category closure of an association | Association |
object_category_closure | 0..* OntologyClass |
Used to hold the object category closure of an association | Association |
subject_namespace | 0..1 String |
Used to hold the subject namespace of an association | Association |
object_namespace | 0..1 String |
Used to hold the object namespace of an association | Association |
subject_label_closure | 0..* String |
Used to hold the subject label closure of an association | Association |
object_label_closure | 0..* String |
Used to hold the object label closure of an association | Association |
retrieval_source_ids | 0..* RetrievalSource |
A list of retrieval sources that served as a source of knowledge expressed in... | Association |
id | 1..1 String |
A unique identifier for an entity | Entity |
iri | 0..1 IriType |
An IRI for an entity | Entity |
category | 0..* CategoryType |
Name of the high level ontology class in which this entity is categorized | Entity |
type | 0..* String |
rdf:type of biolink:Association should be fixed at rdf:Statement | Entity |
name | 0..1 LabelType |
A human-readable name for an attribute or entity | Entity |
description | 0..1 NarrativeText |
a human-readable description of an entity | Entity |
has_attribute | 0..* Attribute |
connects any entity to an attribute | Entity |
has_count | 0..1 Integer |
number of things with a particular property | FrequencyQuantifier |
has_total | 0..1 Integer |
total number of things in a particular reference set | FrequencyQuantifier |
has_quotient | 0..1 Double |
FrequencyQuantifier | |
has_percentage | 0..1 Double |
equivalent to has quotient multiplied by 100 | FrequencyQuantifier |
severity_qualifier | 0..1 SeverityValue |
a qualifier used in a phenotypic association to state how severe the phenotyp... | EntityToFeatureOrDiseaseQualifiersMixin |
onset_qualifier | 0..1 Onset |
a qualifier used in a phenotypic association to state when the phenotype appe... | EntityToFeatureOrDiseaseQualifiersMixin |
frequency_qualifier | 0..1 FrequencyValue |
a qualifier used in a phenotypic association to state how frequent the phenot... | FrequencyQualifierMixin |
Identifier and Mapping Information
Schema Source
- from schema: https://w3id.org/biolink/biolink-model
Mappings
Mapping Type | Mapped Value |
---|---|
self | biolink:GeneAsAModelOfDiseaseAssociation |
native | biolink:GeneAsAModelOfDiseaseAssociation |
LinkML Source
Direct
name: gene as a model of disease association
from_schema: https://w3id.org/biolink/biolink-model
is_a: gene to disease association
mixins:
- model to disease association mixin
- entity to disease association mixin
slot_usage:
subject:
name: subject
description: A gene that has a role in modeling the disease. This may be a model
organism ortholog of a known disease gene, or it may be a gene whose mutants
recapitulate core features of the disease.
domain_of:
- association
range: gene or gene product
defining_slots:
- subject
- predicate
- object