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Class: SequenceVariantModulatesTreatmentAssociation

An association between a sequence variant and a treatment or health intervention. The treatment object itself encompasses both the disease and the drug used.

  • NOTE: this is an abstract class and should not be instantiated directly

URI: biolink:SequenceVariantModulatesTreatmentAssociation

classDiagram class SequenceVariantModulatesTreatmentAssociation Association <|-- SequenceVariantModulatesTreatmentAssociation SequenceVariantModulatesTreatmentAssociation : aggregator_knowledge_source SequenceVariantModulatesTreatmentAssociation : category SequenceVariantModulatesTreatmentAssociation : description SequenceVariantModulatesTreatmentAssociation : has_attribute SequenceVariantModulatesTreatmentAssociation --|> attribute : has_attribute SequenceVariantModulatesTreatmentAssociation : has_evidence SequenceVariantModulatesTreatmentAssociation --|> evidence type : has_evidence SequenceVariantModulatesTreatmentAssociation : id SequenceVariantModulatesTreatmentAssociation : iri SequenceVariantModulatesTreatmentAssociation : knowledge_source SequenceVariantModulatesTreatmentAssociation : name SequenceVariantModulatesTreatmentAssociation : negated SequenceVariantModulatesTreatmentAssociation : object SequenceVariantModulatesTreatmentAssociation --|> treatment : object SequenceVariantModulatesTreatmentAssociation : object_category SequenceVariantModulatesTreatmentAssociation --|> ontology class : object_category SequenceVariantModulatesTreatmentAssociation : object_category_closure SequenceVariantModulatesTreatmentAssociation --|> ontology class : object_category_closure SequenceVariantModulatesTreatmentAssociation : object_closure SequenceVariantModulatesTreatmentAssociation : object_label_closure SequenceVariantModulatesTreatmentAssociation : object_namespace SequenceVariantModulatesTreatmentAssociation : original_object SequenceVariantModulatesTreatmentAssociation : original_predicate SequenceVariantModulatesTreatmentAssociation : original_subject SequenceVariantModulatesTreatmentAssociation : predicate SequenceVariantModulatesTreatmentAssociation : primary_knowledge_source SequenceVariantModulatesTreatmentAssociation : publications SequenceVariantModulatesTreatmentAssociation --|> publication : publications SequenceVariantModulatesTreatmentAssociation : qualifiers SequenceVariantModulatesTreatmentAssociation --|> ontology class : qualifiers SequenceVariantModulatesTreatmentAssociation : retrieval_source_ids SequenceVariantModulatesTreatmentAssociation --|> retrieval source : retrieval_source_ids SequenceVariantModulatesTreatmentAssociation : subject SequenceVariantModulatesTreatmentAssociation --|> sequence variant : subject SequenceVariantModulatesTreatmentAssociation : subject_category SequenceVariantModulatesTreatmentAssociation --|> ontology class : subject_category SequenceVariantModulatesTreatmentAssociation : subject_category_closure SequenceVariantModulatesTreatmentAssociation --|> ontology class : subject_category_closure SequenceVariantModulatesTreatmentAssociation : subject_closure SequenceVariantModulatesTreatmentAssociation : subject_label_closure SequenceVariantModulatesTreatmentAssociation : subject_namespace SequenceVariantModulatesTreatmentAssociation : timepoint SequenceVariantModulatesTreatmentAssociation : type

Inheritance

Slots

Name Cardinality and Range Description Inheritance
subject 1..1
SequenceVariant		 variant that modulates the treatment of some disease Association
predicate 1..1
PredicateType		 A high-level grouping for the relationship type Association
object 1..1
Treatment		 treatment whose efficacy is modulated by the subject variant Association
negated 0..1
Boolean		 if set to true, then the association is negated i Association
qualifiers 0..*
OntologyClass		 connects an association to qualifiers that modify or qualify the meaning of t... Association
publications 0..*
Publication		 One or more publications that report the statement expressed in an Associati... Association
has_evidence 0..*
EvidenceType		 connects an association to an instance of supporting evidence Association
knowledge_source 0..1
String		 An Information Resource from which the knowledge expressed in an Association ... Association
primary_knowledge_source 0..1
String		 The most upstream source of the knowledge expressed in an Association that an... Association
aggregator_knowledge_source 0..*
String		 An intermediate aggregator resource from which knowledge expressed in an Asso... Association
timepoint 0..1
TimeType		 a point in time Association
original_subject 0..1
String		 used to hold the original subject of a relation (or predicate) that an extern... Association
original_predicate 0..1
Uriorcurie		 used to hold the original relation/predicate that an external knowledge sourc... Association
original_object 0..1
String		 used to hold the original object of a relation (or predicate) that an externa... Association
subject_category 0..1
OntologyClass		 Used to hold the biolink class/category of an association Association
object_category 0..1
OntologyClass		 Used to hold the biolink class/category of an association Association
subject_closure 0..*
String		 Used to hold the subject closure of an association Association
object_closure 0..*
String		 Used to hold the object closure of an association Association
subject_category_closure 0..*
OntologyClass		 Used to hold the subject category closure of an association Association
object_category_closure 0..*
OntologyClass		 Used to hold the object category closure of an association Association
subject_namespace 0..1
String		 Used to hold the subject namespace of an association Association
object_namespace 0..1
String		 Used to hold the object namespace of an association Association
subject_label_closure 0..*
String		 Used to hold the subject label closure of an association Association
object_label_closure 0..*
String		 Used to hold the object label closure of an association Association
retrieval_source_ids 0..*
RetrievalSource		 A list of retrieval sources that served as a source of knowledge expressed in... Association
id 1..1
String		 A unique identifier for an entity Entity
iri 0..1
IriType		 An IRI for an entity Entity
category 0..*
CategoryType		 Name of the high level ontology class in which this entity is categorized Entity
type 0..*
String		 rdf:type of biolink:Association should be fixed at rdf:Statement Entity
name 0..1
LabelType		 A human-readable name for an attribute or entity Entity
description 0..1
NarrativeText		 a human-readable description of an entity Entity
has_attribute 0..*
Attribute		 connects any entity to an attribute Entity

Comments

  • An alternate way to model the same information could be via a qualifier

Identifier and Mapping Information

Schema Source

  • from schema: https://w3id.org/biolink/biolink-model

Mappings

Mapping Type Mapped Value
self biolink:SequenceVariantModulatesTreatmentAssociation
native biolink:SequenceVariantModulatesTreatmentAssociation

LinkML Source

Direct

name: sequence variant modulates treatment association
description: An association between a sequence variant and a treatment or health intervention.
  The treatment object itself encompasses both the disease and the drug used.
comments:
- An alternate way to model the same information could be via a qualifier
from_schema: https://w3id.org/biolink/biolink-model
is_a: association
abstract: true
slot_usage:
  subject:
    name: subject
    description: variant that modulates the treatment of some disease
    domain_of:
    - association
    range: sequence variant
  object:
    name: object
    description: treatment whose efficacy is modulated by the subject variant
    domain_of:
    - association
    range: treatment
defining_slots:
- subject
- object