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Class: SiRNA

A small RNA molecule that is the product of a longer exogenous or endogenous dsRNA, which is either a bimolecular duplex or very long hairpin, processed (via the Dicer pathway) such that numerous siRNAs accumulate from both strands of the dsRNA. SRNAs trigger the cleavage of their target molecules.

URI: biolink:SiRNA

classDiagram class SiRNA NoncodingRNAProduct <|-- SiRNA SiRNA : available_from SiRNA --|> DrugAvailabilityEnum : available_from SiRNA : category SiRNA : description SiRNA : full_name SiRNA : has_attribute SiRNA --|> attribute : has_attribute SiRNA : has_biological_sequence SiRNA : has_chemical_role SiRNA --|> chemical role : has_chemical_role SiRNA : id SiRNA : in_taxon SiRNA --|> organism taxon : in_taxon SiRNA : in_taxon_label SiRNA : iri SiRNA : is_metabolite SiRNA : is_toxic SiRNA : max_tolerated_dose SiRNA : name SiRNA : provided_by SiRNA : synonym SiRNA : trade_name SiRNA --|> chemical entity : trade_name SiRNA : type SiRNA : xref

Inheritance

Slots

Name Cardinality and Range Description Inheritance
synonym 0..*
LabelType		 Alternate human-readable names for a thing GeneProductMixin, NamedThing
xref 0..*
Uriorcurie		 A database cross reference or alternative identifier for a NamedThing or edge... GeneProductMixin, NamedThing
has_biological_sequence 0..1
BiologicalSequence		 connects a genomic feature to its sequence GenomicEntity
in_taxon 0..*
OrganismTaxon		 connects an entity to its taxonomic classification ThingWithTaxon
in_taxon_label 0..1
LabelType		 The human readable scientific name for the taxon of the entity ThingWithTaxon
id 1..1
String		 A unique identifier for an entity Entity, OntologyClass
is_metabolite 0..1
Boolean		 indicates whether a molecular entity is a metabolite MolecularEntity
trade_name 0..1
ChemicalEntity		 ChemicalEntity
available_from 0..*
DrugAvailabilityEnum		 ChemicalEntity
max_tolerated_dose 0..1
String		 The highest dose of a drug or treatment that does not cause unacceptable side... ChemicalEntity
is_toxic 0..1
Boolean		 ChemicalEntity
has_chemical_role 0..*
ChemicalRole		 A role is particular behaviour which a chemical entity may exhibit ChemicalEntity
provided_by 0..*
String		 The value in this node property represents the knowledge provider that create... NamedThing
full_name 0..1
LabelType		 a long-form human readable name for a thing NamedThing
iri 0..1
IriType		 An IRI for an entity Entity
category 1..*
CategoryType		 Name of the high level ontology class in which this entity is categorized Entity
type 0..*
String		 Entity
name 0..1
SymbolType		 genes are typically designated by a short symbol and a full name Entity, MacromolecularMachineMixin
description 0..1
NarrativeText		 a human-readable description of an entity Entity
has_attribute 0..*
Attribute		 connects any entity to an attribute Entity

Aliases

  • small interfering RNA
  • RNAi

Identifier and Mapping Information

Valid ID Prefixes

Instances of this class should have identifiers with one of the following prefixes:

  • MIR

  • HGNC

  • WormBase

Schema Source

  • from schema: https://w3id.org/biolink/biolink-model

Mappings

Mapping Type Mapped Value
self biolink:SiRNA
native biolink:SiRNA
exact SO:0000646, WIKIDATA:Q203221

LinkML Source

Direct

name: siRNA
id_prefixes:
- MIR
- HGNC
- WormBase
description: A small RNA molecule that is the product of a longer exogenous or endogenous
  dsRNA, which is either a bimolecular duplex or very long hairpin, processed (via
  the Dicer pathway) such that numerous siRNAs accumulate from both strands of the
  dsRNA. SRNAs trigger the cleavage of their target molecules.
in_subset:
- model_organism_database
from_schema: https://w3id.org/biolink/biolink-model
aliases:
- small interfering RNA
- RNAi
exact_mappings:
- SO:0000646
- WIKIDATA:Q203221
is_a: noncoding RNA product