Class: VariantToDiseaseAssociation

classDiagram class VariantToDiseaseAssociation VariantToEntityAssociationMixin <|-- VariantToDiseaseAssociation EntityToDiseaseAssociationMixin <|-- VariantToDiseaseAssociation Association <|-- VariantToDiseaseAssociation VariantToDiseaseAssociation <|-- VariantAsAModelOfDiseaseAssociation VariantToDiseaseAssociation : aggregator_knowledge_source VariantToDiseaseAssociation : category VariantToDiseaseAssociation : description VariantToDiseaseAssociation : frequency_qualifier VariantToDiseaseAssociation : has_attribute VariantToDiseaseAssociation --|> attribute : has_attribute VariantToDiseaseAssociation : has_evidence VariantToDiseaseAssociation --|> evidence type : has_evidence VariantToDiseaseAssociation : id VariantToDiseaseAssociation : iri VariantToDiseaseAssociation : knowledge_source VariantToDiseaseAssociation : name VariantToDiseaseAssociation : negated VariantToDiseaseAssociation : object VariantToDiseaseAssociation --|> disease : object VariantToDiseaseAssociation : object_category VariantToDiseaseAssociation --|> ontology class : object_category VariantToDiseaseAssociation : object_category_closure VariantToDiseaseAssociation --|> ontology class : object_category_closure VariantToDiseaseAssociation : object_closure VariantToDiseaseAssociation : object_label_closure VariantToDiseaseAssociation : object_namespace VariantToDiseaseAssociation : onset_qualifier VariantToDiseaseAssociation --|> onset : onset_qualifier VariantToDiseaseAssociation : original_object VariantToDiseaseAssociation : original_predicate VariantToDiseaseAssociation : original_subject VariantToDiseaseAssociation : predicate VariantToDiseaseAssociation : primary_knowledge_source VariantToDiseaseAssociation : publications VariantToDiseaseAssociation --|> publication : publications VariantToDiseaseAssociation : qualifiers VariantToDiseaseAssociation --|> ontology class : qualifiers VariantToDiseaseAssociation : retrieval_source_ids VariantToDiseaseAssociation --|> retrieval source : retrieval_source_ids VariantToDiseaseAssociation : severity_qualifier VariantToDiseaseAssociation --|> severity value : severity_qualifier VariantToDiseaseAssociation : subject VariantToDiseaseAssociation --|> sequence variant : subject VariantToDiseaseAssociation : subject_category VariantToDiseaseAssociation --|> ontology class : subject_category VariantToDiseaseAssociation : subject_category_closure VariantToDiseaseAssociation --|> ontology class : subject_category_closure VariantToDiseaseAssociation : subject_closure VariantToDiseaseAssociation : subject_label_closure VariantToDiseaseAssociation : subject_namespace VariantToDiseaseAssociation : timepoint VariantToDiseaseAssociation : type

name: variant to disease association
comments:
- TODO decide no how to model pathogenicity
from_schema: https://w3id.org/biolink/biolink-model
is_a: association
mixins:
- variant to entity association mixin
- entity to disease association mixin
slot_usage:
  subject:
    name: subject
    description: a sequence variant in which the allele state is associated in some
      way with the disease state
    examples:
    - value: CLINVAR:52241
      description: NM_000059.3(BRCA2):c.7007G>C (p.Arg2336Pro)
    domain_of:
    - association
  predicate:
    name: predicate
    description: E.g. is pathogenic for
    domain_of:
    - predicate mapping
    - association
    subproperty_of: related condition
  object:
    name: object
    description: a disease that is associated with that variant
    examples:
    - value: MONDO:0016419
      description: hereditary breast cancer
    domain_of:
    - association
defining_slots:
- subject
- object