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Slot: contraindicated_in

Holds between a substance, procedure, or activity and a medical condition or circumstance, where an authority has established that the substance, procedure, or activity should not be applied as an intervention in patients with the condition or circumstance because it can result in detrimental outcomes.

URI: biolink:contraindicated_in

Inheritance

Properties

Identifier and Mapping Information

Annotations

property value
canonical_predicate True

Schema Source

  • from schema: https://w3id.org/biolink/biolink-model

LinkML Source

name: contraindicated in
annotations:
  canonical_predicate:
    tag: canonical_predicate
    value: true
  opposite_of:
    tag: opposite_of
    value: treats
description: Holds between a substance, procedure, or activity and a medical condition
  or circumstance, where an authority  has established that the substance, procedure,
  or activity should not be applied as an intervention in patients  with the condition
  or circumstance because it can result in detrimental outcomes.
notes:
- This predicate relates the intervention with a specific disease, phenotype, or other
  medical circumstance that  puts patients at high risk for detrimental outcomes.  This
  may be a different condition from the one that the  drug would be used to treat
  (e.g.  pseudoephedrine is contraindicated in people with high-blood pressure as  a
  treatment for nasal congestion), a biological state (e.g. isotretinoin is contraindicated
  in people who  are pregnant as a treatment for acne), or being on a different medication
  (e.g. aspirin is contraindicated  in people taking warfarrin as a preventative treatment
  for stroke).
from_schema: https://w3id.org/biolink/biolink-model
exact_mappings:
- NCIT:C37933
is_a: related to at instance level
domain: chemical or drug or treatment
multivalued: true
inherited: true
alias: contraindicated_in
range: disease or phenotypic feature