Slot: max_tolerated_dose
The highest dose of a drug or treatment that does not cause unacceptable side effects. The maximum tolerated dose is determined in clinical trials by testing increasing doses on different groups of people until the highest dose with acceptable side effects is found. Also called MTD.
URI: biolink:max_tolerated_dose
Inheritance
- node_property
- max_tolerated_dose
Applicable Classes
| Name | Description | Modifies Slot |
|---|---|---|
| ChemicalEntity | A chemical entity is a physical entity that pertains to chemistry or biochemi... | no |
| MolecularEntity | A molecular entity is a chemical entity composed of individual or covalently ... | no |
| SmallMolecule | A small molecule entity is a molecular entity characterized by availability i... | no |
| ChemicalMixture | A chemical mixture is a chemical entity composed of two or more molecular ent... | no |
| NucleicAcidEntity | A nucleic acid entity is a molecular entity characterized by availability in ... | no |
| MolecularMixture | A molecular mixture is a chemical mixture composed of two or more molecular e... | no |
| ComplexMolecularMixture | A complex molecular mixture is a chemical mixture composed of two or more mol... | no |
| ProcessedMaterial | A chemical entity (often a mixture) processed for consumption for nutritional... | no |
| Drug | A substance intended for use in the diagnosis, cure, mitigation, treatment, o... | no |
| EnvironmentalFoodContaminant | no | |
| FoodAdditive | no | |
| Food | A substance consumed by a living organism as a source of nutrition | no |
| Exon | A region of the transcript sequence within a gene which is not removed from t... | no |
| Transcript | An RNA synthesized on a DNA or RNA template by an RNA polymerase | no |
| CodingSequence | no | |
| RNAProduct | no | |
| RNAProductIsoform | Represents a protein that is a specific isoform of the canonical or reference... | no |
| NoncodingRNAProduct | no | |
| MicroRNA | no | |
| SiRNA | A small RNA molecule that is the product of a longer exogenous or endogenous ... | no |
Properties
- Range: String
Identifier and Mapping Information
Schema Source
- from schema: https://w3id.org/biolink/biolink-model
LinkML Source
name: max tolerated dose
description: The highest dose of a drug or treatment that does not cause unacceptable
side effects. The maximum tolerated dose is determined in clinical trials by testing
increasing doses on different groups of people until the highest dose with acceptable
side effects is found. Also called MTD.
from_schema: https://w3id.org/biolink/biolink-model
is_a: node property
domain: named thing
multivalued: false
alias: max_tolerated_dose
domain_of:
- chemical entity
range: string