Slot: treats
Holds between a substance, procedure, or activity and a medical condition (disease or phenotypic feature), and states that the substance, procedure, or activity is able to ameliorate, stabilize, or cure the condition or delay, prevent, or reduce the risk of it manifesting in the first place. ‘Treats’ edges should be asserted (knoweldge_level: assertion) only in cases where there is strong supporting evidence - i.e. the intervention is approved or in phase 4 trials for the condition, or is a well-established treatment in the medical community. In the absence of such evidence, weaker predicates should be used in asserted edges (e.g. ‘in clinical trials for’ or ‘beneficial in models of’). ‘Treats’ edges based on weaker or indirect forms of evidence can however be created as predictions (knowledge_level: prediction) and should point to the more foundational asserted edges that support them.
URI: biolink:treats
Mixin Usage
| mixed into | description | range | domain |
|---|---|---|---|
| ameliorates_condition | Holds between an entity and an existing medical condition (disease or phenoty... | disease or phenotypic feature | |
| preventative_for_condition | Holds between a substance, procedure, or activity and a medical condition (di... | disease or phenotypic feature |
Properties
-
Range: DiseaseOrPhenotypicFeature
-
Mixin: True
Aliases
- is substance that treats
- indicated for
- ameliorates or prevents condition
Identifier and Mapping Information
Annotations
| property | value |
|---|---|
| canonical_predicate | True |
Schema Source
- from schema: https://w3id.org/biolink/biolink-model
LinkML Source
name: treats
annotations:
canonical_predicate:
tag: canonical_predicate
value: true
description: 'Holds between a substance, procedure, or activity and a medical condition
(disease or phenotypic feature), and states that the substance, procedure, or activity
is able to ameliorate, stabilize, or cure the condition or delay, prevent, or reduce
the risk of it manifesting in the first place. ‘Treats’ edges should be asserted (knoweldge_level:
assertion) only in cases where there is strong supporting evidence - i.e. the intervention
is approved or in phase 4 trials for the condition, or is a well-established treatment
in the medical community. In the absence of such evidence, weaker predicates should
be used in asserted edges (e.g. ‘in clinical trials for’ or ‘beneficial in models
of’). ‘Treats’ edges based on weaker or indirect forms of evidence can however
be created as predictions (knowledge_level: prediction) and should point to the
more foundational asserted edges that support them.'
in_subset:
- translator_minimal
from_schema: https://w3id.org/biolink/biolink-model
aliases:
- is substance that treats
- indicated for
- ameliorates or prevents condition
exact_mappings:
- DRUGBANK:treats
- SEMMEDDB:TREATS
- WIKIDATA_PROPERTY:P2175
related_mappings:
- MONDO:disease_responds_to
narrow_mappings:
- RO:0002606
- NCIT:regimen_has_accepted_use_for_disease
- REPODB:clinically_tested_approved_unknown_phase
- REPODB:clinically_tested_suspended_phase_0
- REPODB:clinically_tested_suspended_phase_1
- REPODB:clinically_tested_suspended_phase_1_or_phase_2
- REPODB:clinically_tested_suspended_phase_2
- REPODB:clinically_tested_suspended_phase_2_or_phase_3
- REPODB:clinically_tested_suspended_phase_3
- REPODB:clinically_tested_terminated_phase_0
- REPODB:clinically_tested_terminated_phase_1
- REPODB:clinically_tested_terminated_phase_1_or_phase_2
- REPODB:clinically_tested_terminated_phase_2
- REPODB:clinically_tested_terminated_phase_2_or_phase_3
- REPODB:clinically_tested_terminated_phase_3
- REPODB:clinically_tested_withdrawn_phase_0
- REPODB:clinically_tested_withdrawn_phase_1
- REPODB:clinically_tested_withdrawn_phase_1_or_phase_2
- REPODB:clinically_tested_withdrawn_phase_2
- REPODB:clinically_tested_withdrawn_phase_2_or_phase_3
- REPODB:clinically_tested_withdrawn_phase_3
- SNOMED:plays_role
broad_mappings:
- DRUGBANK:treats
- SEMMEDDB:TREATS
- WIKIDATA_PROPERTY:P2175
- MONDO:disease_responds_to
mixin: true
domain: chemical or drug or treatment
alias: treats
range: disease or phenotypic feature