Enum: DruggableGeneCategoryEnum
URI: DruggableGeneCategoryEnum
Permissible Values
Value |
Meaning |
Description |
tclin |
None |
These targets have activities in DrugCentral (ie |
tbio |
None |
These targets have activities in ChEMBL, Guide to Pharmacology or DrugCentral... |
tchem |
None |
These targets do not have known drug or small molecule activities that satisf... |
tdark |
None |
These are targets about which virtually nothing is known |
Slots
Schema Source
- from schema: https://w3id.org/biolink/biolink-model
LinkML Source
name: DruggableGeneCategoryEnum
from_schema: https://w3id.org/biolink/biolink-model
permissible_values:
tclin:
text: tclin
description: These targets have activities in DrugCentral (ie. approved drugs)
with known mechanism of action.
tbio:
text: tbio
description: These targets have activities in ChEMBL, Guide to Pharmacology or
DrugCentral that satisfy the activity thresholds detailed below.
tchem:
text: tchem
description: 'These targets do not have known drug or small molecule activities
that satisfy the activity thresholds detailed below AND satisfy one or more
of the following criteria: target is above the cutoff criteria for Tdark target
is annotated with a Gene Ontology Molecular Function or Biological Process leaf
term(s) with an Experimental Evidence code'
tdark:
text: tdark
description: 'These are targets about which virtually nothing is known. They do
not have known drug or small molecule activities that satisfy the activity thresholds
detailed below AND satisfy two or more of the following criteria: A PubMed text-mining
score from Jensen Lab less than 5, greater than or equal TO 3 Gene RIFs, or
less than or equal to 50 Antibodies available according to http://antibodypedia.com.'